SUMO2/3 MODIFICATION OF TRANSCRIPTION-ASSOCIATED PROTEINS CONTROLS CELL VIABILITY IN RESPONSE TO OXYGEN AND GLUCOSE DEPRIVATION-MEDIATED STRESS

SUMO2/3 modification of transcription-associated proteins controls cell viability in response to oxygen and glucose deprivation-mediated stress

Abstract Because limited oxygen Intermittent Closed-System Catheters and glucose supply to tissues is a serious challenge that cells must properly measure to decide between surviving or triggering cell death, organisms have developed accurate mechanisms for sensing and signaling these conditions.In recent years, signaling through posttranslational

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A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model

Abstract Background In order to better understand the multifactorial nature of osteoporosis, animal models Turntables are utilized and compared to healthy controls.Female sheep are well established as a model for osteoporosis induced by ovariectomy, calcium and vitamin D low diet, application of steroids, or a combination of these treatments.Transc

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Protein post-translational modification regulates HIV-1 latency

AIDS is a disease named acquired immunodeficiency syndrome, which caused by the human immunodeficiency virus (HIV).HIV can be divided into HIV type 1 (HIV-1) and HIV type 2 (HIV-2).HIV-1 is a global pandemic that has caused serious harm.Although the application of combination antiretroviral therapy (cART) can prolong the life of patients, HIV-1 inf

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